Heart damage

Doxorubicin, epirubicin, and some other drugs may cause permanent heart damage (calledcardiomyopathy). The risk of this occurring depends on how much of the drug is given, and is highest if the drug is used for a long time or in high doses. Doctors watch closely for this side effect. Most doctors check the patient’s heart function (with a test like a MUGA or echocardiogram) before starting one of these drugs. They also carefully control the doses and watch for symptoms of heart problems, and may repeat the heart test to monitor heart function during treatment. If the heart function begins to decline, treatment with these drugs is stopped. In some patients, heart damage takes a long time to develop. They may not show signs of poor heart function until months or years after treatment ends. Heart damage from these drugs happens more often if other drugs can cause heart damage, such as trastuzumab and other drugs that target HER2 are used as well, so doctors are more cautious when these drugs are used together.


Hand-foot syndrome

Chemo brain

Increased risk of leukemia

Feeling unwell or tired


Hormone therapy for breast cancer in men

Targeted therapy for breast cancer in men

Bone-directed therapy for breast cancer in men


Coping and support for male breast cancer


Related Topics

Benign breast conditions

General breast cancer terms

Types of breast cancer in men







Oncologists, Breast Surgeons are the specialists who deal with the breast cancer